Resolving cardiometabolic dysfunction with transient gene therapy
Foment Bio’s platform of off-the-shelf gene therapy constructs activate in vivo regenerative exosome production to resolve tissue injury.
Our Approach…
The field of regenerative medicine has made enormous strides in its understanding of the biology of healing over the last few decades. Focus has evolved from stem cells to secreted paracrine factors and exosomes as being the key regulators of tissue remodeling in response to injury and inflammation.
As we age, our repair signals in response to injury become dysregulated and insufficient to achieve complete healing. Over time, or in response to substantial injury, unresolved tissue injury presents as a chronic condition.
Foment’s transient gene therapy drives in vivo production of regenerative exosomes leading to enhanced tissue healing and long-term remodeling.